Old Dominion may refer to:
- Old Dominion, nickname for the U.S. Commonwealth of Virginia
- Old Dominion, Virginia, an unincorporated community in Albemarle County, Virginia
Organizations
- Old Dominion Brewing Company
- Old Dominion Electric Cooperative
- Old Dominion Freight Line
- Old Dominion University, a public university in Norfolk, Virginia
- Old Dominion Monarchs and Lady Monarchs, the athletic teams representing Old Dominion University
- Old Dominion Foundation, a predecessor of the Andrew W. Mellon Foundation
Music
- Old Dominion (band), an American country-rock band
- "Old Dominion", the debut EP of Indie rock band Hotel of the Laughing Tree
- "Old Dominion", a song by Avail from their 2000 album One Wrench
- "Old Dominion", a song by Enon from their 2002 album High Society
Others
- Old Dominion (Amtrak), former Amtrak passenger train
- Old Dominion Athletic Conference, an NCAA Division III athletic conference
- Old Dominions, commonly used as a reference to parts of the British Empire